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iS CLINICAL Active Serum

Active Serum

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This top-rated serum evens skin tone, treats blemishes, and reduces the appearance of fine lines and wrinkles. The combination of botanically-sourced exfoliators and skin brighteners provide both immediate and long-term results. Appropriate for most skin types (except very sensitive or fragile), Active Serum also reduces the appearance of pores. 

The key ingredients in Active Serum are skin brighteners (Arbutin and Mushroom Extract), and the botanical extracts related to glycolic and salicylic acids. 

As a brand, iS Clinical is dedicated to enriching overall skin health with scientifically advanced, clinically proven formulas. All iS Clinical products are botanically based, non-systemic, formulations. These potent botanical ingredients are gentle but effective and do not get absorbed and cross into the blood system. 

1oz / 30mL
0.5oz / 15mL

Why We Love It

Active Serum has the well-deserved status as the top-selling product for IS Clinical. We recommend it as a fast-acting hydroxy acid serum to cleanse pores and improve skin texture. It is great for acne-prone clients or those looking for an overall glow. Use it at night, followed by an appropriate moisturizer. 

We often recommend our clients purchase IS Clinical Super Serum (Vitamin C) to use in the morning, and Active Serum to use at night. This combination is a great anti-aging routine that is no-fuss.


Apply sparingly to clean skin, smoothing over face and neck (or as directed). This "active" product will produce a slight tingling sensation, which should dissipate within a few minutes.


Water/Aqua/Eau, Glycerin, Glyceryl Polyacrylate, Butylene Glycol, SD Alcohol 30, Saccharum Officinarum (Sugar Cane) Extract, Vaccinium Myrtillus (Bilberry) Extract, Triethanolamine, Arbutin, Salix Alba (Willow) Bark Extract, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol.

  • Medical Grade
  • Patient Tested
  • Hand Selected
  • Products We

This is an excellent preventative product to begin in your twenties.

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